Joseph or Joe McDonald may refer to:
* Joseph A. McDonald (1866–1930), American businessman influential in the steel industry
* Joseph E. McDonald (1819–1891), U.S. Representative and Senator from Indiana
*Joseph P. McDonald (1919–1994), U.S. Army Air Corps private instrumental in the Imperial Japanese Navy Air Service's attack on Pearl Harbor
* Country Joe McDonald (born 1942), lead singer of the 1960s psychedelic rock group Country Joe & the Fish
* Joe McDonald (baseball executive) (born 1929), former front office executive in American Major League Baseball
* Joe McDonald (footballer) (1929–2003), Scottish footballer who played for Sunderland and the Scotland national football team
* Joe McDonald (politician) (born 1966), Minnesota state representative and master photographer
* Joe McDonald (third baseman) (1888–1963), Major League Baseball third baseman who played in 1910 with the St. Louis Browns
* Joe McDonald (mobster) (1917–1997), Irish-American gangster of the Winter Hill Gang
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